Dif`fer*en"ti*ate (?), v. t. 1. To distinguish or mark by a specific difference; to effect a difference in, as regards classification; to develop differential characteristics in; to specialize; to desynonymize.

The word then was differentiated into the two forms then and than.

Two or more of the forms assumed by the same original word become differentiated in signification.
Dr. Murray.

2. To express the specific difference of; to describe the properties of (a thing) whereby it is differenced from another of the same class; to discriminate. Earle.

3. (Math.) To obtain the differential, or differential coefficient, of; as, to differentiate an algebraic expression, or an equation.

Dif`fer*en"ti*ate, v. i. (Biol.) To acquire a distinct and separate character. Huxley.