Lethargize

Leth"ar*gize (lĕth"ȧr*jīz), v. t. [imp. & p. p. Lethargized (- jīzd); p. pr. & vb. n. Lethargizing (- jī`zĭng).] To make lethargic.

All bitters are poison, and act by stilling, and depressing, and lethargizing the irritability.
Coleridge.