Vi*cis"si*tude (?), n. [L.
vicissitudo, fr. vicis change, turn: cf. F.
vicissitude. See Vicarious.]
1. Regular change or succession from one thing to
another; alternation; mutual succession; interchange.
God made two great lights . . .
To illuminate the earth and rule the day
In their vicissitude, and rule the night.
Milton.
2. Irregular change; revolution;
mutation.
This man had, after many vicissitudes of fortune,
sunk at last into abject and hopeless poverty.
Macaulay.